ZAVEDOS 1MG/ML VIAL 1 Solution for injection 5ml Vial

Zavedos 1mg/ml Solution for Injection is an essential medication used in the treatment of various types of leukemia.
This potent antineoplastic agent, containing Idarubicin hydrochloride, is administered intravenously by healthcare professionals to combat cancer cells.
As a crucial component of chemotherapy regimens, Zavedos aims to induce remission and improve patient outcomes in acute myeloid leukemia (AML) and other leukemias.

Benefits of Use

Zavedos 1mg/ml Solution for Injection offers significant benefits in oncology:

• Highly effective in the treatment of acute myeloid leukemia (AML).
• Used in combination with other chemotherapeutic agents for enhanced efficacy.
• Aims to achieve complete remission in patients with newly diagnosed or relapsed leukemia.
• Part of standard protocols for induction and consolidation therapy in certain leukemias.

How to Use

Zavedos is a prescription-only medication and must be administered by a qualified healthcare professional in a clinical setting.

1. Zavedos 1mg/ml solution is prepared for intravenous infusion.
2. The dosage and duration of treatment are determined by the patient's medical condition, body surface area, and response to therapy, as well as the specific chemotherapy protocol.
3. It is typically administered over a short period into a flowing intravenous infusion.
4. Close monitoring of blood counts, cardiac function, and liver/kidney function is required throughout the treatment course.

Caution & Warnings

• Bone Marrow Suppression: Zavedos causes severe bone marrow suppression, leading to anemia, leukopenia, and thrombocytopenia. Regular complete blood counts are essential.
• Cardiotoxicity: Risk of cardiac toxicity, including congestive heart failure. Cardiac function should be assessed before and during treatment.
• Extravasation: Avoid extravasation as it can lead to severe local tissue necrosis. Administer through a central venous line if possible.
• Infections: Due to immunosuppression, patients are at increased risk of severe infections.
• Pregnancy and Lactation: Contraindicated in pregnancy and breastfeeding due to potential fetal harm. Effective contraception must be used during and after treatment.
• Liver and Kidney Impairment: Dosage adjustments may be necessary in patients with impaired liver or kidney function.
• Secondary Malignancies: There is an increased risk of developing secondary acute myeloid leukemia.

Ingredients

• Active Ingredient: Idarubicin hydrochloride 1mg/ml.
• Excipients: Sodium chloride, hydrochloric acid (for pH adjustment), sodium hydroxide (for pH adjustment), water for injections.

Product Details

• Brand: ZAVEDOS
• Manufacturer: Pfizer
• Strength: 1 mg/ml
• Dosage Form: Solution for injection
• Package Size: 5ml Vial (1 vial)
• Administration Route: Intravenous