In stock
Paclitaxel Kabi 6 mg/ml Solution for injection 43.4ml Vial
In stock
Only 1 left
SKU
10331014193
Paclitaxel Kabi 6 mg/ml Solution for Injection is an antineoplastic agent used in chemotherapy for various cancers, including ovarian, breast, and non-small cell lung cancer. This 43.4ml vial, containing Paclitaxel, works by inhibiting cancer cell division. It is for intravenous administration by healthcare professionals.
Product Overview
Paclitaxel Kabi 6 mg/ml Solution for Injection is a potent antineoplastic agent widely used in various chemotherapy regimens. Developed by Fresenius Kabi, a global leader in healthcare, this medication contains Paclitaxel, a taxane compound that interferes with the growth of cancer cells by disrupting microtubule function, leading to cell death. It is provided as a sterile solution in a 43.4ml vial, intended for intravenous infusion.
Benefits of Use
Paclitaxel Kabi is an essential component in the treatment of several types of cancer, offering significant therapeutic benefits:
- Effective in the treatment of ovarian cancer, including advanced stages.
- Used for breast cancer, both as adjuvant therapy and for metastatic disease.
- Indicated for non-small cell lung cancer (NSCLC) in combination with cisplatin or as monotherapy.
- Approved for AIDS-related Kaposi's sarcoma when other treatments have failed.
- Works by inhibiting cell division, thereby slowing down or stopping the growth and spread of cancer cells.
How to Use
Paclitaxel Kabi 6 mg/ml Solution for Injection is a prescription medication that must be administered by a qualified healthcare professional in a clinical setting.
- The medication is administered as an intravenous (IV) infusion, typically over 3 to 24 hours, depending on the specific treatment protocol.
- Patients are usually pre-medicated with corticosteroids (e.g., dexamethasone), antihistamines (e.g., diphenhydramine), and H2 antagonists (e.g., ranitidine) to prevent hypersensitivity reactions.
- Dosage and frequency of administration are determined by the physician based on the patient's specific cancer type, stage, body surface area, and overall health.
- The solution must be diluted before use, usually in 0.9% sodium chloride injection, 5% dextrose injection, or 5% dextrose and 0.9% sodium chloride injection.
- Monitoring of blood counts and liver function is crucial during treatment.
Caution & Warnings
Before using Paclitaxel Kabi, please note the following important warnings:
- Administration should only be performed under the supervision of a physician experienced in antineoplastic chemotherapy.
- Severe hypersensitivity reactions (anaphylaxis) can occur, requiring immediate medical attention.
- Bone marrow suppression (neutropenia, thrombocytopenia, anemia) is a dose-limiting toxicity; frequent blood counts are necessary.
- Peripheral neuropathy is common and can be severe; monitor for symptoms like tingling, numbness, and pain.
- Cardiovascular effects, including bradycardia, may occur.
- Avoid use during pregnancy and breastfeeding due to potential harm to the fetus or infant. Women of childbearing potential should use effective contraception during and after treatment.
- Patients with severe liver impairment may require dose adjustments.
- Care must be taken to avoid extravasation (leakage of the drug into surrounding tissues) during infusion, which can cause severe local reactions.
- Do not administer to patients with a baseline neutrophil count of less than 1.5 x 10^9/L.
Ingredients
- Active Ingredient: Paclitaxel 6 mg/ml
- Excipients: Macrogolglycerol ricinoleate (Cremophor EL or polyoxyethylated castor oil), Dehydrated ethanol, Anhydrous citric acid.
Product Details
Paclitaxel Kabi 6 mg/ml Solution for Injection is presented as a clear, colorless to slightly yellow viscous solution. Each 43.4ml vial contains 260.4 mg of Paclitaxel. It is designed for single-use and requires dilution prior to intravenous administration. The product maintains its stability under specific storage conditions, ensuring its efficacy until the expiration date. As a critical component in oncology, it adheres to stringent pharmaceutical manufacturing standards.
| Gtin | 603257001 |
|---|---|
| Recommended Sale Price | 1354.15 |
| Is Wasfaty Product | No |
| Brand | Not Defined |
| Ingredient Name | PACLITAXEL |
| SFDA Reg. No | 603257001 |
| IBC | 603257001 |
| Drug Type | Prescription |
| Scientific Name | Paclitaxel |
| Strength | 6 mg/ml |
| Strength Unit | mg/ml |
| Form | Solution for injection |
| Admin Route | Intravenous |
| Size | 43.4 |
| Size Unit | ml |
| Package Types | Vial |
| Package Size | 43.4ml |
| shelfLife | 3 years (unopened vial) |
| Storage conditions | Store below 25°C. Keep the vial in the outer carton in order to protect from light. Do not refrigerate or freeze the undiluted concentrate. |
| Refrigerator Storage | No |
| Distribute area | Global |
Products you might like
