CARBOPLATIN EBEWE 50MG-5ML 10 mg/ml Concentrate for solution for infusion 45ml Vial

Product Overview

Carboplatin "Ebewe" 10 mg/ml Concentrate for solution for infusion is an antineoplastic agent (chemotherapy drug) used in the treatment of various types of cancer.
It belongs to the platinum compounds group, which works by interfering with the DNA of cancer cells, thereby inhibiting their growth and division.
This 45ml vial is designed for intravenous administration by healthcare professionals.

Benefits of Use

• Effective against a wide range of solid tumors, including ovarian, lung, and head and neck cancers.
• A crucial component in many established chemotherapy regimens globally.
• Generally associated with a lower incidence of nephrotoxicity (kidney damage) compared to its analogue, cisplatin.
• Manufactured by Ebewe Pharma, a trusted name in oncology and critical care pharmaceuticals.

How to Use

Carboplatin "Ebewe" is a specialized medication that must be administered strictly under the supervision of a qualified healthcare professional in a clinical setting.

1. The concentrate is typically diluted with appropriate infusion solutions (e.g., 5% Dextrose Injection, 0.9% Sodium Chloride Injection) before administration.
2. It is administered as an intravenous infusion over a specified period, as determined by the physician.
3. Dosage and duration of treatment are highly individualized, based on the specific type of cancer, patient's body surface area or glomerular filtration rate, bone marrow reserve, and overall health status.
4. Regular monitoring of blood counts, kidney function, and other vital parameters is essential throughout the treatment course.

Caution & Warnings

• Must only be administered by physicians experienced in antineoplastic chemotherapy and in facilities equipped to handle potential complications.
• Causes myelosuppression (bone marrow depression), leading to a decrease in white blood cells, red blood cells, and platelets. Frequent hematological monitoring is required.
• Hypersensitivity reactions, including anaphylaxis, can occur, especially after prior exposure to platinum-containing agents. Emergency equipment and personnel should be readily available.
• Neurotoxicity (peripheral neuropathy) and ototoxicity (hearing impairment) are possible side effects and require careful monitoring.
• Caution should be exercised in patients with pre-existing renal impairment, and dosage adjustments may be necessary.
• Contraindicated in patients with severe bone marrow depression, severe renal impairment, or a history of severe allergic reactions to carboplatin or other platinum-containing compounds.
• Should not be used during pregnancy or lactation due to potential harm to the fetus or infant. Women of childbearing potential should use effective contraception during and after treatment.
• Avoid contact with skin and mucous membranes. Use appropriate protective measures during preparation and administration.

Ingredients

• Active Ingredient: Carboplatin
• Inactive Ingredients: Water for injection

Product Details

• Concentration: 10 mg/ml
• Volume: 45ml per vial
• Form: Concentrate for solution for infusion
• Manufacturer: Ebewe Pharma (part of Sandoz)
• Administration Route: Intravenous