NOREPIRIN 2 MG/ML 4ML AMPOUL 10 PCS

Norepirin 2 mg/mL Ampoules contain Norepinephrine Bitartrate, a critical medication primarily used in emergency and intensive care settings.

This potent drug is an adrenergic agonist, specifically designed to raise and maintain blood pressure in patients suffering from severe acute hypotension (low blood pressure) due to conditions such as septic shock, myocardial infarction, or general anesthesia.

It acts rapidly by stimulating alpha-adrenergic receptors, leading to vasoconstriction and increased systemic vascular resistance, thereby improving myocardial contractility and coronary blood flow.

Norepirin is crucial for stabilizing hemodynamics in life-threatening situations where blood pressure support is immediately required to ensure adequate organ perfusion.

Benefits of Use

• Rapidly elevates and maintains blood pressure in hypotensive states.
• Improves systemic vascular resistance and cardiac output.
• Essential for managing shock conditions, including septic and cardiogenic shock.
• Supports vital organ perfusion during critical illness.

How to Use

Norepirin 2 mg/mL Ampoules are for intravenous administration only and should be administered by qualified medical professionals in a controlled clinical environment.

1. Norepirin is typically diluted in 5% Dextrose Injection or 0.9% Sodium Chloride Injection prior to administration.
2. It is administered via continuous intravenous infusion, preferably through a central venous catheter.
3. The dosage is highly individualized and titrated according to the patient's blood pressure response and clinical condition.
4. Blood pressure, heart rate, and other hemodynamic parameters must be continuously monitored throughout treatment.
5. Avoid abrupt discontinuation; dosage should be gradually tapered under medical supervision.

Caution & Warnings

• For hospital and critical care use only.
• Strict monitoring of blood pressure, heart rate, and tissue perfusion is essential during infusion.
• Extravasation (leakage into surrounding tissue) can cause severe local tissue necrosis; ensure proper venous access and monitor infusion site closely.
• Use with extreme caution in patients with peripheral or mesenteric vascular thrombosis, as it may increase ischemia.
• Interactions with MAO inhibitors, tricyclic antidepressants, and certain antihistamines may potentiate vasopressor effects, leading to severe hypertension.
• Not for use as a sole treatment for hypovolemia; administer fluid resuscitation concurrently.

Ingredients

• Active Ingredient: Norepinephrine Bitartrate (equivalent to Norepinephrine 2 mg/mL)
• Excipients: Water for Injection, Sodium Chloride

Product Details

• Brand: NOREPIRIN
• Strength: 2 mg/mL
• Volume per Ampoule: 4 mL
• Package Size: 10 Ampoules
• Form: Solution for Injection
• Administration Route: Intravenous