NOREPINEPHRINE 1MG/ML AMPULE 10 PCS

Product Overview

Norepinephrine 1mg/mL Ampules are a critical care medication used to manage severe hypotension (critically low blood pressure) arising from various shock states, including septic shock and cardiogenic shock.

This potent medication functions as a vasoconstrictor and an inotropic agent.

It works by stimulating alpha-adrenergic receptors, leading to widespread vasoconstriction and an increase in systemic vascular resistance.

Additionally, it acts on beta-1 adrenergic receptors, enhancing myocardial contractility and ultimately improving cardiac output.

Its rapid action makes it indispensable in life-threatening circulatory collapse situations to stabilize patient hemodynamics.

Benefits of Use

• Rapidly elevates blood pressure in patients suffering from acute hypotension.

• Enhances myocardial contractility, contributing to improved cardiac output.

• Crucial for stabilizing cardiovascular function during severe shock states.

• Helps restore adequate tissue perfusion in critically ill patients.

How to Use

1. Norepinephrine 1mg/mL Ampules are strictly for intravenous (IV) administration.

2. It should always be administered via a central venous catheter to minimize the risk of extravasation.

3. The dosage is highly individualized, titrated by a healthcare professional based on the patient's blood pressure response and clinical condition.

4. Typically, treatment begins with a low continuous intravenous infusion rate, which is then adjusted as required.

5. Continuous monitoring of blood pressure, heart rate, cardiac output, and tissue perfusion is essential throughout administration.

6. Always dilute the ampule content according to hospital protocols and clinical guidelines before infusion.

Caution & Warnings

• Administer only under the direct supervision of trained healthcare professionals in a well-monitored clinical setting.

• Extravasation (leakage into surrounding tissue) can cause severe local tissue necrosis; ensure proper intravenous access and frequently inspect the infusion site.

• Use with extreme caution in patients with pre-existing peripheral vascular disease, mesenteric or renal vascular thrombosis, or any condition where vasoconstriction could compromise vital organ perfusion.

• Avoid abrupt discontinuation of therapy, as this can lead to a precipitous drop in blood pressure and circulatory collapse.

• Monitor for potential adverse effects including arrhythmias, severe hypertension, headache, reflex bradycardia, and anxiety.

• Solutions containing norepinephrine should be inspected visually for particulate matter and discoloration prior to administration. Do not use if the solution is discolored or contains a precipitate.

Ingredients

Active Ingredient: Norepinephrine (as Norepinephrine bitartrate).

Inactive Ingredients: May include sodium chloride, water for injection, and other excipients to adjust pH and maintain stability (e.g., sodium metabisulfite as an antioxidant, if present).

Product Details

Form: Solution for Injection

Strength: 1 mg/mL

Package Size: 10 Ampules

Drug Type: Prescription Only Medicine (POM)

Storage Conditions: Store below 25°C. Protect from light. Do not freeze.