Mannitol 20% Infusion IV 500 ML Bottle - SPIMACO

Mannitol 20% Infusion, presented in a 500 ml IV bottle by SPIMACO, is a critical pharmaceutical solution utilized in various medical emergencies and therapeutic interventions. This sterile, pyrogen-free solution is an osmotic diuretic designed for intravenous administration.

As referenced on leading pharmaceutical platforms like NahdiOnline, Mannitol is a highly effective agent for managing conditions associated with elevated intracranial pressure (ICP) and intraocular pressure (IOP). Its mechanism involves drawing fluid from tissues into the vascular space, thereby promoting diuresis and reducing swelling.

Benefits of Use:

• Effective reduction of elevated intracranial pressure, particularly in neurological emergencies and post-trauma situations.
• Significant lowering of intraocular pressure, beneficial in acute glaucoma or during ophthalmic surgical procedures.
• Promotes forced diuresis to aid in the excretion of toxic substances from the body and prevent acute renal failure in certain clinical settings.
• Helps in the management of cerebral edema by reducing fluid accumulation in brain tissues.

How to Use:

1. Mannitol 20% Infusion is for intravenous administration only and must be administered by a qualified healthcare professional.
2. The dosage and rate of infusion are determined by the patient's age, weight, clinical condition, and therapeutic response.
3. Close monitoring of vital signs, electrolyte balance, renal function, and fluid status is essential during infusion.
4. The solution should be visually inspected for particulate matter and discoloration prior to administration. Do not use if solution is cloudy or contains particles.
5. Administer using a filtered intravenous set to prevent crystal formation from entering the patient's bloodstream.

Caution & Warnings:

• Hypersensitivity: Do not administer to patients with known hypersensitivity to Mannitol.
• Renal Impairment: Use with extreme caution in patients with pre-existing renal disease or impaired renal function. Close monitoring of renal output is crucial.
• Fluid & Electrolyte Imbalance: May cause significant fluid and electrolyte disturbances, including hyponatremia, hypokalemia, and dehydration. Regular electrolyte monitoring is necessary.
• Cardiac Failure: Use with caution in patients with severe congestive heart failure as rapid fluid shifts can exacerbate cardiac conditions.
• Anuria: Contraindicated in patients with established anuria (absence of urine formation) due to severe renal disease.
• Crystallization: Mannitol solutions may crystallize at low temperatures. If crystallization occurs, warm the bottle in a water bath to redissolve the crystals before use.

Ingredients:

Each 100 ml contains:

• Mannitol: 20 g
• Water for Injection: q.s. (quantum sufficit) to 100 ml

Product Details:

• Product Name: Mannitol 20% Infusion
• Form: Intravenous Solution
• Strength: 20% w/v
• Volume: 500 ml
• Container Type: IV Bottle
• Manufacturer: Saudi Pharmaceutical Industries & Medical Appliances Corp. (SPIMACO)
• Legal Status: Prescription Only Medicine (POM)
• Storage: Store at controlled room temperature, protected from extreme heat and freezing.