MAGNESIUM SULFATE I.V. 50 % PU 50 ML VIAL PSI

Magnesium Sulfate I.V. 50% - 50 mL Vial by PharmaSource Inc.

Magnesium Sulfate I.V. 50% is a sterile, nonpyrogenic solution of magnesium sulfate heptahydrate in water for injection, designed for intravenous use.

Each 50 mL vial contains 50% magnesium sulfate, providing a concentrated source of this essential electrolyte.

This medication is crucial in various clinical settings, including the management of severe hypomagnesemia, seizure prophylaxis in pre-eclampsia and eclampsia, and certain cardiac arrhythmias.

It acts as a physiological calcium antagonist and a depressant of the central nervous system.

As referenced on leading pharmaceutical platforms like Nahdi Online, , and , Magnesium Sulfate is a vital injectable medication used widely in hospitals and clinical environments.

Benefits of Use:

• Effective treatment for acute magnesium deficiency (hypomagnesemia).
• Primary intervention for the prevention and control of seizures in pre-eclampsia and eclampsia.
• Used in the management of specific cardiac arrhythmias, particularly Torsades de Pointes.
• Can be utilized as a bronchodilator in severe acute asthma exacerbations.
• Contributes to muscle relaxation and nerve function regulation.

How to Use:

1. Magnesium Sulfate I.V. 50% must only be administered by qualified healthcare professionals.
2. The solution is intended for intravenous administration after appropriate dilution.
3. Dosage and administration rate depend on the patient's condition, magnesium levels, and therapeutic objective.
4. Careful monitoring of vital signs, magnesium levels, and renal function is required during infusion.
5. Always inspect the vial for particulate matter and discoloration before administration; do not use if present.
6. Ensure compatibility with other intravenous solutions and medications if co-administering.

Caution & Warnings:

• Prescription Only: This medication is for prescription use only and must be administered under medical supervision.
• Renal Impairment: Use with extreme caution in patients with impaired renal function, as magnesium excretion may be reduced, leading to hypermagnesemia.
• Cardiac Effects: Rapid intravenous administration can cause hypotension and cardiac depression. Monitor ECG and blood pressure closely.
• Neuromuscular Blockade: Potentiates the effects of neuromuscular blocking agents.
• Respiratory Depression: High doses can lead to respiratory depression; have calcium gluconate (antidote) readily available.
• Pregnancy and Lactation: Use during pregnancy for conditions like pre-eclampsia/eclampsia is established, but caution is advised in other contexts. Consult a physician.
• Drug Interactions: Be aware of potential interactions with central nervous system depressants, calcium channel blockers, and neuromuscular blockers.
• Administration: Never administer undiluted solution directly by rapid intravenous push due to the risk of magnesium toxicity.

Ingredients:

• Active Ingredient: Magnesium Sulfate Heptahydrate
• Excipients: Water for Injection

Product Details:

• Form: Sterile Solution for Injection
• Strength: 50% (500 mg/mL)
• Volume: 50 mL per vial
• Packaging: Single-use glass vial
• Manufacturer: PharmaSource Inc.
• Storage: Store at controlled room temperature, 20C to 25C (68F to 77F). Protect from freezing.