BREZTRI AEROSPHERE 160/7.2/5 mcg Inhalation Suspension, 120 Doses

BREZTRI AEROSPHERE 160/7.2/5 mcg is an advanced triple therapy inhalation suspension, meticulously formulated for the daily maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD).

Available as a 120-dose metered-dose inhaler, this medication expertly combines an inhaled corticosteroid (ICS), a long-acting muscarinic antagonist (LAMA), and a long-acting beta2-agonist (LABA).

This powerful combination works synergistically to significantly improve lung function, reduce the frequency of COPD exacerbations, and enhance the overall quality of life for patients.

It is a vital component in the management of moderate to severe COPD symptoms, helping patients breathe easier and maintain their daily activities.

Product Overview

BREZTRI AEROSPHERE is specifically designed for long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and/or emphysema.

Its unique formulation delivers three active ingredients in a single inhaler, offering comprehensive respiratory management.

Key Benefits

• Triple action formula: Combines an ICS, LAMA, and LABA for comprehensive COPD management.
• Improved lung function: Helps to open airways, reduce inflammation, and facilitate easier breathing.
• Reduced exacerbations: Significantly lowers the risk of COPD flare-ups and hospitalizations.
• Convenient once-daily dosing: Simplifies the treatment regimen, promoting better adherence.
• Designed for long-term maintenance: Provides consistent and sustained symptom control.
• Enhances quality of life: Helps patients manage symptoms effectively, allowing for greater daily activity.

How to Use

1. Read the Patient Information Leaflet and Instructions for Use carefully before starting treatment.
2. Prime the inhaler before first use or if it has not been used for more than 7 days, by shaking well and releasing 4 test sprays into the air away from your face.
3. Shake the inhaler well immediately before each use.
4. Exhale fully through your mouth, emptying your lungs as much as possible.
5. Place the mouthpiece in your mouth, closing your lips tightly around it.
6. As you start to inhale slowly and deeply through your mouth, press down firmly on the top of the inhaler to release a dose.
7. Continue to inhale deeply and steadily for as long as you can.
8. Remove the inhaler from your mouth and hold your breath for about 10 seconds, or for as long as is comfortable.
9. Exhale slowly.
10. If a second dose is prescribed, wait at least 30 seconds, then repeat steps 3-9.
11. Rinse your mouth with water and spit it out after each use to help prevent oral thrush. Do not swallow the water.
12. Clean the inhaler regularly as per manufacturer instructions provided in the leaflet.

Caution & Warnings

• Not for acute relief: BREZTRI AEROSPHERE is for maintenance treatment only and should not be used to relieve sudden breathing problems. Use a fast-acting rescue inhaler for acute symptoms.
• Consult your doctor: Do not stop using this medicine or change your dose without consulting your doctor, even if you feel better.
• Risk of pneumonia: Inhaled corticosteroids may increase the risk of pneumonia in people with COPD. Monitor for signs and symptoms of pneumonia.
• Eye problems: May cause new or worsened glaucoma or cataracts. Regular eye examinations are recommended, especially for patients with a history of these conditions.
• Urinary retention: May cause or worsen urinary retention. Use with caution in patients with prostatic hyperplasia or bladder-neck obstruction.
• Cardiovascular effects: Use with caution in patients with cardiovascular disorders due to potential for cardiovascular effects associated with beta2-agonists.
• Immunosuppression: Long-term use of corticosteroids may lead to immunosuppression and increased susceptibility to infections.
• Hypersensitivity reactions: Seek immediate medical attention if you experience signs of an allergic reaction (e.g., rash, hives, swelling of the face, mouth, or tongue, breathing problems).
• Drug interactions: Inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and other inhalers, to avoid potential interactions.

Ingredients

• Active Ingredients: Each actuation delivers 160 mcg of Budesonide, 7.2 mcg of Glycopyrronium (equivalent to 5.8 mcg of glycopyrronium), and 5 mcg of Formoterol Fumarate Dihydrate.
• Inactive Ingredients: Norflurane (HFA-227ea), Ethanol, Glycine.

Product Details

• Brand: BREZTRI AEROSPHERE
• Manufacturer: AstraZeneca
• Drug Type: Prescription Medicine
• Form: Inhalation Suspension (Metered-dose inhaler)
• Administration Route: Inhalation
• Strength: 160/7.2/5 mcg
• Package Size: 1 Inhaler, 120 Doses
• Storage: Store at controlled room temperature (20-25°C), protect from direct sunlight or freezing temperatures.