GONAL-f 75 IU Powder for Solution for Injection

GONAL-f 75 IU (Follitropin alfa) is a highly purified recombinant human follicle-stimulating hormone (r-hFSH) produced by Merck Serono, a leader in fertility treatments.

This medication is essential for individuals undergoing specific fertility therapies, designed to stimulate and support reproductive functions.

Product Overview

As referenced on and other leading e-commerce platforms like and , GONAL-f 75 IU comes as a lyophilized powder for solution for injection.

It plays a crucial role in stimulating ovarian follicular development in women and spermatogenesis in men, offering hope and advanced treatment options for infertility.

Each pack contains one vial of powder, designed for single-use subcutaneous administration after reconstitution.

Benefits of Use

• Stimulates ovarian follicular development in women with hypogonadotropic hypogonadism, anovulation, or those undergoing Assisted Reproductive Technologies (ART) such as IVF.
• Induces ovulation in anovulatory women who have been unresponsive to clomifene citrate.
• Stimulates spermatogenesis in men with hypogonadotropic hypogonadism when used in conjunction with human chorionic gonadotropin (hCG).
• A well-established and trusted medication in fertility clinics worldwide, backed by extensive clinical research.

How to Use

1. GONAL-f 75 IU should only be administered under the supervision of a physician experienced in the treatment of fertility problems.
2. The powder must be reconstituted with the provided solvent (sterile water for injection) immediately prior to use.
3. Carefully follow the instructions for reconstitution and injection provided by your healthcare professional or in the patient information leaflet.
4. Administer the solution via subcutaneous injection, usually into the abdomen or thigh.
5. Rotate the injection site daily to prevent localized reactions.
6. Dosage and duration of treatment will be individually tailored by your doctor based on your specific condition and response to treatment.
7. Do not mix with other medications in the same syringe.

Caution & Warnings

• Ovarian Hyperstimulation Syndrome (OHSS): Be vigilant for signs of OHSS, a potentially serious condition. Symptoms include severe pelvic pain, nausea, vomiting, abdominal distension, and weight gain. Contact your doctor immediately if these occur.

• Multiple Pregnancies: Treatment with GONAL-f increases the risk of multiple pregnancies, which carry higher risks for both mother and babies.

• Ectopic Pregnancy: Women with a history of tubal disease are at an increased risk of ectopic pregnancy.

• Thromboembolic Events: Women with general risk factors for thrombosis, such as a personal or family history of thromboembolism, may have an increased risk during or after treatment.

• Allergic Reactions: Rarely, allergic reactions to the active substance or excipients may occur. Seek immediate medical attention if you experience symptoms like rash, itching, swelling, severe dizziness, or trouble breathing.

• Contraindications: Do not use GONAL-f if you have primary ovarian failure, uncontrolled non-gonadal endocrinopathies (e.g., thyroid or adrenal dysfunction), tumors of the pituitary gland or hypothalamus, hormone-dependent tumors of the reproductive organs, or abnormal uterine bleeding of undetermined origin.

• Always inform your doctor about all other medications you are taking and any pre-existing medical conditions.

Ingredients

• Active Ingredient: Follitropin alfa (recombinant human Follicle Stimulating Hormone, r-hFSH) 75 International Units (IU).
• Excipients: Sucrose, Sodium dihydrogen phosphate monohydrate, Disodium phosphate dihydrate, Methionine, Polysorbate 20, Phosphoric acid, Sodium hydroxide.

Product Details

• Brand: Gonal-f
• Manufacturer: Merck Serono
• Dosage Form: Powder for solution for injection
• Strength: 75 IU
• Route of Administration: Subcutaneous
• Package Size: 1 vial of powder for solution for injection
• Drug Type: Prescription only medicine