Paclitaxel Kabi 6 mg/ml Solution for injection 50ml Vial

Product Overview

Paclitaxel Kabi 6 mg/ml Solution for Injection is a potent antineoplastic agent, part of the taxane class of chemotherapy drugs, used in the treatment of various cancers. It works by interfering with the normal function of microtubules, structures essential for cell division, thereby inhibiting the growth and spread of cancer cells.

This medication is manufactured by Fresenius Kabi, a leading pharmaceutical company known for its commitment to healthcare solutions. It is designed for intravenous administration under strict medical supervision.

Benefits of Use

• Effective in treating a wide range of solid tumors, including ovarian cancer, breast cancer, non-small cell lung cancer, and AIDS-related Kaposi's sarcoma.
• Can be used as a primary treatment or in combination with other chemotherapy agents.
• Helps in slowing the progression of cancer and improving patient outcomes in suitable cases.

How to Use

1. Paclitaxel Kabi must be administered by a qualified healthcare professional experienced in the use of antineoplastic agents.
2. The solution for injection is designed to be diluted before intravenous infusion.
3. The dosage and administration schedule are highly individualized and depend on the type of cancer, disease stage, patient's body surface area, and overall health status.
4. Patients typically receive premedication (e.g., corticosteroids, antihistamines, H2-blockers) prior to paclitaxel infusion to minimize the risk of hypersensitivity reactions.
5. Close monitoring of vital signs and blood counts is essential throughout the treatment period.

Caution & Warnings

• Hypersensitivity Reactions: Severe and potentially fatal hypersensitivity reactions can occur. Patients must be carefully monitored, especially during the first and subsequent infusions.
• Myelosuppression: Bone marrow suppression (neutropenia, thrombocytopenia, anemia) is a major dose-limiting toxicity. Regular blood count monitoring is crucial.
• Peripheral Neuropathy: Can cause peripheral neuropathy, which may be severe and dose-dependent.
• Cardiac Abnormalities: Bradycardia, myocardial ischemia, and other cardiac events have been reported.
• Liver Impairment: Exercise caution in patients with hepatic impairment; dose adjustments may be necessary.
• Pregnancy and Breastfeeding: Not recommended during pregnancy due to potential fetal harm. Women of childbearing potential should use effective contraception. Breastfeeding is contraindicated.
• Not for Self-Administration: This medication requires specialized handling and administration in a clinical setting.

Ingredients

• Active Ingredient: Paclitaxel 6 mg/ml
• Excipients: Macrogolglycerol ricinoleate (Cremophor EL), dehydrated alcohol (ethanol), citric acid.

Product Details

• Manufacturer: Fresenius Kabi
• Form: Concentrate for solution for infusion
• Strength: 6 mg/ml
• Package Size: 50 ml vial
• Therapeutic Class: Antineoplastic agent, Taxane