OXALIPLATIN MEDAC 150MG POWDER 150 Powder for solution for infusion Vial

Product Description

OXALIPLATIN MEDAC 150MG POWDER for solution for infusion is a vital chemotherapeutic agent specifically designed for the treatment of various cancers. As an antineoplastic drug, Oxaliplatin works by interfering with the DNA of cancer cells, thereby preventing their growth and spread. This medication is prepared as a powder and reconstituted into a solution for intravenous administration, ensuring precise and controlled delivery to patients under strict medical supervision.

This product is commonly used in combination with other chemotherapy drugs to enhance its efficacy, particularly in the management of advanced colorectal cancer. It is crucial for administration to be carried out by qualified healthcare professionals in a clinical setting due to its potent nature and the requirement for careful monitoring of patients for potential side effects. OXALIPLATIN MEDAC embodies Medac GmbH's commitment to providing essential cancer treatments, supporting patients in their fight against the disease.

Benefits of Use

• Effective in the treatment of metastatic colorectal cancer, often in combination with fluorouracil and leucovorin.
• May also be used for adjuvant treatment of stage III colon cancer after complete resection of the primary tumor.
• Targets and inhibits the growth of cancer cells by damaging their DNA.
• Administered intravenously for rapid and systemic action.

How to Use

1. OXALIPLATIN MEDAC is for intravenous administration only and must be prepared and administered by qualified personnel experienced in cytotoxic handling.
2. The powder must be reconstituted with sterile water for injection or 5% glucose solution as per manufacturer guidelines to form a concentrated solution.
3. This concentrated solution is then diluted further in 250 to 500 mL of 5% glucose solution before infusion.
4. The recommended dose is typically calculated based on the patient's body surface area (BSA) and administered over 2 to 6 hours.
5. Pre-medication, such as antiemetics and corticosteroids, may be given to manage potential side effects like nausea, vomiting, and allergic reactions.
6. Regular monitoring of blood counts, kidney function, liver function, and neurological status is essential during treatment.

Caution & Warnings

• This medication must only be administered under the supervision of a physician experienced in chemotherapy.
• Severe neurological side effects, including peripheral sensory neuropathy, can occur and may be irreversible.
• Myelosuppression (bone marrow depression), including neutropenia, thrombocytopenia, and anemia, is a common and potentially severe side effect requiring frequent blood count monitoring.
• Hypersensitivity reactions, including anaphylaxis, can occur, particularly after several cycles of treatment. Facilities for managing anaphylaxis must be readily available.
• Renal and hepatic impairment may require dose adjustments.
• Pregnancy and breastfeeding: Oxaliplatin is contraindicated during pregnancy and breastfeeding due to potential fetal harm. Effective contraception is required for both male and female patients during and after treatment.
• Avoid contact with skin or mucous membranes during handling; use appropriate protective equipment.
• Do not mix with alkaline solutions or chloride-containing solutions (e.g., sodium chloride 0.9%) as it can lead to precipitation.

Ingredients

Active Ingredient: Oxaliplatin 150 mg.

Excipients: Not specified in general product name, but typical for powder for solution might include specific acids or inert fillers for stability. Refer to the official package leaflet for full excipient list.

Product Details

• Form: Powder for solution for infusion.
• Strength: 150 mg per vial.
• Administration Route: Intravenous.
• Brand: MEDAC.
• Manufacturer: MEDAC GmbH.
• Drug Type: Prescription Only Medicine (POM).