METHOTREXATE EBEWE 100MG-ML VIAL 10 ml

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Product Overview

Methotrexate Ebewe 100mg/ml is a highly potent medication provided in a 10ml vial, containing a concentrated solution for injection. This vital pharmaceutical product is manufactured by EBEWE Pharma GmbH, a company renowned for its commitment to high-quality therapeutic solutions, often part of the Sandoz/Novartis group. Primarily used as an antimetabolite, antineoplastic, and immunosuppressant, it plays a crucial role in treating various severe medical conditions. As a prescription-only medicine (POM), its use requires strict medical supervision and careful dosage management.

Benefits of Use

1. Effective treatment for various types of cancer, including leukemias, lymphomas, osteosarcoma, breast cancer, and lung cancer. 2. Manages severe, active rheumatoid arthritis in adults when other treatments have failed. 3. Provides relief for severe, debilitating psoriasis that is unresponsive to other therapies. 4. Acts as an immunosuppressant, useful in certain autoimmune disorders to reduce inflammation and immune system overactivity.

How to Use

Methotrexate Ebewe 100mg/ml solution is for parenteral administration and must be administered by a qualified healthcare professional.

1. The exact dosage and administration schedule will be determined by your doctor based on your medical condition, body surface area, and treatment protocol.
2. It can be administered intravenously (IV), intramuscularly (IM), or subcutaneously (SC), depending on the specific indication.
3. Strict adherence to the prescribed dosage and administration route is critical to ensure efficacy and minimize adverse effects.
4. Regular monitoring through blood tests and other diagnostic procedures will be conducted by your healthcare provider during treatment.
5. Do not self-administer this medication.

Caution & Warnings

• Methotrexate can cause severe and potentially fatal adverse reactions, including bone marrow suppression, liver toxicity, kidney damage, and lung toxicity.
• This medication is contraindicated in pregnancy and breastfeeding due to its teratogenic effects. Effective contraception must be used by both male and female patients during and after treatment.
• Avoid concurrent use of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), certain antibiotics (e.g., trimethoprim/sulfamethoxazole), and other nephrotoxic or hepatotoxic drugs without consulting your doctor, as this may increase methotrexate toxicity.
• Patients should be closely monitored for signs of infection, as methotrexate can suppress the immune system.
• Regular blood tests (complete blood count, liver function tests, kidney function tests) are essential before and during treatment to monitor for toxicity.
• Patients may require folic acid supplementation, especially in non-oncological indications, to reduce some side effects.
• Report any unusual symptoms immediately to your healthcare provider.

Ingredients

• Active Ingredient: Methotrexate (as disodium salt) 100mg/ml
• Excipients: Sodium Chloride, Sodium Hydroxide (for pH adjustment), Water for Injections.

Product Details

Product Name: Methotrexate Ebewe 100mg/ml VIAL 10ml
Strength: 100 mg/ml
Volume: 10 ml per vial
Dosage Form: Solution for Injection
Manufacturer: EBEWE Pharma GmbH (Sandoz)
Drug Type: Prescription Only Medicine (POM)
Storage: Store below 25°C. Protect from light.