METHOTREXATE "EBEWE" 100MG-ML VIAL

Product Description

Methotrexate "Ebewe" 100mg/mL Vial is a potent prescription medication.
It is primarily utilized in the treatment of various neoplastic diseases (cancers), severe psoriasis that is unresponsive to other therapies, and severe active rheumatoid arthritis when other treatments have failed.

As an antimetabolite, it works by interfering with the growth of certain cells in the body, particularly rapidly multiplying cells such as cancer cells and cells involved in immune system overactivity.

This medication requires careful medical supervision due to its powerful effects and potential side effects, ensuring optimal therapeutic outcomes and patient safety.

Benefits of Use

• Effective in targeting rapidly dividing cells, crucial for cancer therapy.
• Provides significant relief for symptoms of severe rheumatoid arthritis by modulating the immune system.
• Offers a critical treatment option for severe, debilitating psoriasis refractory to other systemic therapies.
• Available in a concentrated solution for flexible dosing and various administration routes.

How to Use

1. Methotrexate "Ebewe" 100mg/mL Solution for injection must be administered by a qualified healthcare professional.
2. The dosage, frequency, and route of administration (intravenous, intramuscular, subcutaneous, or intrathecal) will be determined by your physician based on your medical condition, body weight, and response to treatment.
3. Ensure accurate dilution (if required) and aseptic technique during preparation and administration.
4. Close monitoring of blood counts, liver function, and kidney function is essential throughout the treatment course.

Caution & Warnings

• Serious Side Effects: Methotrexate can cause severe and potentially fatal adverse reactions, including bone marrow suppression, liver toxicity, kidney damage, lung toxicity, and gastrointestinal toxicity. Regular monitoring is crucial.
• Pregnancy and Breastfeeding: Highly contraindicated in pregnancy as it can cause fetal harm or death. Women of childbearing potential must use effective contraception during treatment and for a specified period after. Not recommended during breastfeeding.
• Drug Interactions: Interacts with numerous medications, including NSAIDs, proton pump inhibitors, antibiotics (e.g., trimethoprim/sulfamethoxazole), and retinoids. Inform your doctor of all medications you are taking.
• Infections: May increase the risk of serious infections due to immunosuppression. Avoid live vaccines during treatment.
• Hydration: Maintain adequate hydration to prevent kidney toxicity, especially with high-dose regimens.

Ingredients

• Active Ingredient: Methotrexate (as disodium salt)
• Excipients: Sodium chloride, Sodium hydroxide (for pH adjustment), Water for injection.

Product Details

• Formulation: Solution for injection/infusion.
• Concentration: 100 mg/mL.
• Package Size: Typically supplied as 10 mL vials.
• Manufacturer: Ebewe Pharma (part of Sandoz, a Novartis division).