Madopar 200/50mg 100 Tablets

Madopar 200/50mg is a combination medicine containing Levodopa and Benserazide, specifically formulated to manage the symptoms of Parkinson's disease.
Levodopa is converted to dopamine in the brain, helping to replenish the deficient dopamine levels in Parkinson's patients, thereby improving motor symptoms.
Benserazide prevents the breakdown of Levodopa outside the brain, allowing more Levodopa to reach the brain and reducing side effects.

This medication is crucial for patients experiencing tremors, rigidity, slow movement (bradykinesia), and postural instability associated with Parkinson's disease.
It significantly enhances their quality of life and daily functionality.

Benefits of Use

• Significant improvement in motor symptoms of Parkinson's disease, including tremors, rigidity, and bradykinesia.
• Enhances the ability to perform daily activities.
• Benserazide component reduces peripheral side effects of Levodopa and increases its availability to the brain.
• Helps in managing 'wearing-off' effects experienced by some Parkinson's patients.

How to Use

Always use Madopar 200/50mg exactly as prescribed by your doctor.
The dosage is highly individualized and depends on the severity of your condition and your response to treatment.

1. Initial Dose: Typically, treatment starts with a low dose, which is gradually increased by your doctor.
2. Administration: Tablets should preferably be taken at least 30 minutes before or one hour after meals. Taking it with a small snack may reduce gastrointestinal discomfort.
3. Swallowing: Swallow the tablets whole with a glass of water. Do not chew or crush them unless specifically instructed by your doctor for a particular formulation.
4. Consistency: Take your doses at regular intervals throughout the day as directed by your physician to maintain stable drug levels.
5. Do Not Stop Abruptly: Do not discontinue Madopar suddenly, as this can lead to serious withdrawal symptoms, including a condition similar to Neuroleptic Malignant Syndrome.

Caution & Warnings

• Medical Supervision: This medication must only be used under strict medical supervision.
• Contraindications: Not recommended for patients with narrow-angle glaucoma, severe psychiatric disorders, severe heart disease, liver or kidney impairment, or those taking non-selective MAO inhibitors.
• Side Effects: Common side effects include nausea, vomiting, dizziness, drowsiness, involuntary movements (dyskinesias), and hallucinations. Report any unusual or severe side effects to your doctor.
• Interactions: Inform your doctor about all other medications, supplements, and herbal products you are taking, especially other Parkinson's drugs, antidepressants, and blood pressure medications.
• Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding. Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Driving and Operating Machinery: May cause drowsiness or sudden sleep episodes. Exercise caution when driving or operating machinery.
• Mood Changes: Monitor for changes in mood, behavior, or psychiatric symptoms, and report them to your doctor.

Ingredients

Each tablet contains:

• Levodopa: 200 mg
• Benserazide (as hydrochloride): 50 mg
• Excipients: Microcrystalline cellulose, talc, magnesium stearate, povidone, ethylcellulose, colloidal anhydrous silica, mannitol, iron oxides (E172).

Product Details

• Form: Tablets
• Strength: 200mg Levodopa / 50mg Benserazide
• Package Size: 100 tablets per carton
• Manufacturer: F. Hoffmann-La Roche AG