KIOVIG 100MG/ML SOLUTION FOR INFUSION 100 Solution for infusion 25ml Vial

Product Description

KIOVIG 100mg/mL Solution for Infusion 25ml Vial is a highly specialized medication, essential for patients requiring immune system support or modulation. This intravenous immunoglobulin (IVIg) product is derived from human plasma and contains purified antibodies, primarily immunoglobulin G (IgG). KIOVIG is critically important for individuals with a compromised immune system, providing a robust defense against infections by supplying a broad spectrum of protective antibodies.

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Benefits of Use

• Provides antibodies to individuals with primary immunodeficiency syndromes (PID) who are unable to produce sufficient antibodies on their own.
• Used in secondary immunodeficiencies (SID) in patients with certain diseases or conditions, such as chronic lymphocytic leukemia (CLL) or multiple myeloma, to prevent recurrent infections.
• Modulates the immune system in various autoimmune and inflammatory conditions, including Idiopathic Thrombocytopenic Purpura (ITP), Kawasaki Disease, Guillain-Barré Syndrome (GBS), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), and Multifocal Motor Neuropathy (MMN).
• Helps reduce the frequency and severity of bacterial and viral infections in immunocompromised patients.

How to Use

1. KIOVIG 100mg/mL Solution for Infusion must be administered intravenously only.
2. Administration should always be performed by a healthcare professional in a clinical setting.
3. The dosage and infusion rate will be determined by the treating physician based on the patient's specific condition, body weight, and response to treatment.
4. The solution should be clear or slightly opalescent and colorless to pale yellow. Do not use if the solution is turbid or has particulates.
5. Allow the product to reach room temperature (20°C to 25°C) before administration.
6. Ensure the patient is adequately hydrated before and during the infusion.

Caution & Warnings

• Allergic Reactions: Patients may experience severe allergic or anaphylactic reactions. Monitor closely, especially during the first infusion.
• Kidney Dysfunction: IVIg products can cause acute renal dysfunction. Ensure adequate hydration, especially in patients at risk of kidney problems.
• Thrombotic Events: Blood clots (thrombotic events) have been reported, particularly in patients with risk factors such as advanced age, immobility, or cardiovascular disease.
• Aseptic Meningitis Syndrome (AMS): Symptoms like severe headache, neck stiffness, fever, and photophobia may occur.
• Hemolytic Anemia: IVIg products can cause hemolytic anemia. Monitor for signs and symptoms.
• Transfusion-Related Acute Lung Injury (TRALI): This severe pulmonary complication can occur.
• Infection Risk: Although measures are taken, products derived from human plasma carry a potential risk of transmitting infectious agents.
• Inform your doctor about all medical conditions and medications before starting KIOVIG.
• Do not self-administer this medication.

Ingredients

• Active ingredient: Human Normal Immunoglobulin G (100 mg/mL)
• Other ingredients: Glycine, water for injections.

Product Details

• Concentration: 100 mg/mL
• Volume: 25 mL per vial
• Form: Solution for Infusion
• Storage: Store below 25°C. Do not freeze.
• Manufacturer: Takeda