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Fosaprepitant SPC 150 powder for solution for injection Vial
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10331014318
Fosaprepitant SPC 150mg is an intravenous powder for solution, specifically formulated to prevent chemotherapy-induced nausea and vomiting (CINV). It acts as a prodrug of aprepitant, effectively blocking NK1 receptors to offer significant relief. Administered by healthcare professionals, this medication helps improve patient comfort during cancer treatment.
Fosaprepitant SPC 150mg Powder for Solution for Injection
Fosaprepitant SPC 150mg is a potent antiemetic medication designed specifically for the prevention of chemotherapy-induced nausea and vomiting (CINV).
This product comes as a powder for solution for injection, intended for intravenous administration.
Fosaprepitant is a prodrug of aprepitant, which acts as a selective neurokinin 1 (NK1) receptor antagonist.
By blocking the NK1 receptor, it helps to prevent both acute and delayed phases of CINV, providing significant relief for patients undergoing chemotherapy treatments.
Benefits of Use
- Highly effective in preventing both acute and delayed chemotherapy-induced nausea and vomiting.
- Contributes significantly to improved patient comfort and quality of life during chemotherapy.
- Offers a convenient administration option as a single-dose or multi-day regimen, as prescribed.
- Acts as a prodrug, ensuring sustained antiemetic activity for prolonged protection.
- An essential component of comprehensive CINV prophylaxis protocols.
How to Use
- Fosaprepitant SPC 150mg powder for solution for injection is strictly for intravenous administration.
- Administration must be performed by a qualified healthcare professional in a clinical setting.
- The dosage and administration schedule will be determined by the treating physician based on the specific chemotherapy regimen and patient factors.
- Typically, the medication is reconstituted and diluted prior to infusion.
- It is usually administered before the start of chemotherapy to provide prophylactic antiemetic coverage.
Caution & Warnings
- For intravenous use only. Do not administer by any other route.
- Not recommended for use in patients with known hypersensitivity to aprepitant, fosaprepitant, or any components of the formulation.
- Exercise caution when administering to patients with severe hepatic impairment, as adjustments may be necessary.
- May interact with other medications, particularly those metabolized by or affecting the cytochrome P450 3A4 (CYP3A4) enzyme system.
- Monitor patients for infusion site reactions, including pain, erythema, and swelling.
- Not indicated for the treatment of established nausea and vomiting.
Ingredients
- Active Ingredient: Fosaprepitant Dimeglumine (equivalent to 150 mg of fosaprepitant)
- Excipients: Disodium Edetate, Polysorbate 80, Lactose Monohydrate (or similar bulking agent), Sodium Hydroxide/Hydrochloric Acid (for pH adjustment).
Product Details
- Form: Powder for solution for injection
- Strength: 150 mg
- Administration Route: Intravenous
- Package Type: Vial
- Storage: Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Protect from light.
- Legal Status: Prescription Drug (Rx)
| Gtin | 06286023000188 |
|---|---|
| Recommended Sale Price | 200 |
| Is Wasfaty Product | No |
| Brand | Not Defined |
| Ingredient Name | FOSAPREPITANT DIMEGLUMINE |
| SFDA Reg. No | 902210504 |
| IBC | 06286023000188 |
| Drug Type | Prescription |
| Scientific Name | Fosaprepitant |
| Strength | 150 |
| Strength Unit | mg |
| Form | Powder for solution for injection |
| Admin Route | Intravenous |
| Size | 1 |
| Size Unit | Vial |
| Package Types | Vial |
| Package Size | 1 Vial |
| Storage conditions | Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Protect from light. |
| Refrigerator Storage | No |
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