DOXORUBICIN 2MG/ML SOLUTION FOR INFUSION 2 mg/ml Concentrate for solution for infusion 25ml Vial

Product Overview

Available on leading platforms such as Nahdi Online, , and , Doxorubicin 2 mg/ml Concentrate for Solution for Infusion is a powerful and essential chemotherapy medication.

It is used in the comprehensive treatment of various types of cancer.

This pharmaceutical product is designed to effectively combat malignant cells by interfering with their DNA and RNA synthesis, thereby inhibiting their growth and proliferation.

It is widely recognized for its critical role in oncology, similar to specialized medical supplies found on these reputable platforms.

Each 25ml vial contains a concentrate solution that, when properly prepared and administered, delivers targeted therapeutic action against a spectrum of cancers.

Benefits of Use

• Broad-Spectrum Anticancer Activity: Effective against a wide range of cancers, including breast cancer, ovarian cancer, bladder cancer, lymphomas (e.g., Hodgkin's and non-Hodgkin's), sarcomas, and acute leukemias.
• Potent Antineoplastic Action: Works by intercalating with DNA, inhibiting macromolecular biosynthesis, and causing DNA cleavage by inhibiting topoisomerase II, leading to cancer cell death.
• Established Efficacy: A well-established and frequently used agent in many chemotherapy regimens, demonstrating significant clinical benefit in improving patient outcomes.

How to Use

1. Administration by Professionals: Doxorubicin must be administered strictly by qualified healthcare professionals experienced in the use of antineoplastic agents.
2. Intravenous Infusion: The concentrate is prepared and administered as an intravenous infusion. It should not be given intramuscularly or subcutaneously.
3. Dosage and Regimen: Dosage and administration schedule are highly individualized and depend on the specific type and stage of cancer, the patient's body surface area, renal and hepatic function, and previous or concomitant therapies.
4. Monitoring: Patients require close monitoring during and after infusion for potential adverse reactions and treatment efficacy.
5. Extravasation Precautions: Care must be taken to avoid extravasation, which can lead to severe local tissue damage.

Caution & Warnings

• Cardiotoxicity: Doxorubicin carries a significant risk of cardiotoxicity, including congestive heart failure. Cardiac function must be carefully monitored (e.g., by ECG, LVEF measurements) before and during treatment.
• Myelosuppression: Can cause severe bone marrow suppression, leading to leukopenia, neutropenia, thrombocytopenia, and anemia. Complete blood counts should be performed regularly.
• Nausea and Vomiting: Common side effects; appropriate antiemetic therapy should be administered.
• Hair Loss (Alopecia): Reversible alopecia is a common and anticipated side effect.
• Mucositis/Stomatitis: Inflammation and ulceration of mucous membranes can occur, particularly in the mouth and gastrointestinal tract.
• Extravasation: Should extravasation occur, it can cause severe pain, tissue necrosis, and blistering. Immediate action is required to minimize damage.
• Pregnancy and Breastfeeding: Contraindicated during pregnancy and breastfeeding due to potential harm to the fetus or infant. Women of childbearing potential and men should use effective contraception during and for a period after treatment.
• Liver and Kidney Impairment: Dosage adjustments may be necessary in patients with impaired hepatic or renal function.
• Drug Interactions: Potential for interactions with other medications; disclose all current medications to your healthcare provider.

Ingredients

• Active Ingredient: Doxorubicin Hydrochloride 2 mg/ml
• Excipients: Water for Injections, and other inactive ingredients as per formulation.

Product Details

• Product Name: DOXORUBICIN 2MG/ML SOLUTION FOR INFUSION
• Form: Concentrate for solution for infusion
• Strength: 2 mg/ml
• Volume: 25 ml per vial
• Package Type: Vial
• Drug Type: Prescription Only Medicine (POM)
• Manufacturer: Accord Healthcare
• Storage: Store in a refrigerator (2°C to 8°C). Protect from light. Do not freeze.