Calciumfolinat Sandoz 10MG-ML VIAL 10 mg/ml Solution for injection 10ml Vial

Product Overview: Calciumfolinat Sandoz 10 mg/ml Solution for Injection

Calciumfolinat Sandoz 10 mg/ml Solution for Injection is a vital pharmaceutical product primarily used in oncology settings.
This sterile solution is supplied in a 10ml vial, providing a precise dosage of Calcium Folinate, a derivative of tetrahydrofolic acid and an active metabolite of folic acid.

Key Benefits:

• Methotrexate Antidote: Primarily used as a 'rescue' therapy to counteract the toxic effects of high-dose methotrexate on healthy cells, especially in bone marrow and gastrointestinal mucosa.
• Enhances Chemotherapy: When administered in combination with 5-fluorouracil, Calciumfolinate can enhance the cytotoxic effects of 5-fluorouracil in various cancer treatments.
• Folate Deficiency Management: Can be used to treat megaloblastic anemia due to folate deficiency, particularly when oral administration of folic acid is not feasible.
• Supportive Care: Plays a crucial role in reducing severe side effects of certain chemotherapy regimens, thereby improving patient tolerance and overall treatment outcomes.

How to Use:

1. Calciumfolinat Sandoz must be administered by a qualified healthcare professional.
2. The solution is intended for intravenous (IV) or intramuscular (IM) injection.
3. Dosage and duration of treatment are highly individualized and depend on the specific medical condition being treated, the patient's response, and concomitant therapies (e.g., methotrexate dosage, 5-fluorouracil regimen).
4. Always follow the specific instructions and guidelines provided by your physician or oncology specialist.
5. Dilution may be required for intravenous infusion; consult pharmaceutical guidelines for proper preparation.

Caution & Warnings:

• This medication should only be administered under the direct supervision of a physician experienced in chemotherapy and oncology.
• Careful monitoring of the patient for adverse reactions and efficacy is essential throughout the treatment course.
• Intrathecal administration (injection into the spinal canal) is strictly contraindicated due to the risk of severe neurotoxicity.
• Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, as interactions can occur (e.g., with 5-fluorouracil, co-trimoxazole, pyrimethamine).
• Patients with impaired renal function may require dose adjustments; close monitoring is necessary.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your doctor before use.
• Store the vial in its outer carton to protect from light and maintain efficacy.

Ingredients:

• Active Ingredient: Calcium folinate (equivalent to folinic acid).
• Excipients: Sodium chloride, hydrochloric acid (for pH adjustment), sodium hydroxide (for pH adjustment), water for injections.

Product Details:

• Brand: Sandoz
• Manufacturer: Sandoz
• Strength: 10 mg/ml
• Volume: 10 ml per vial
• Form: Solution for Injection
• Package Type: Vial
• Storage: Store below 25°C, protect from light.
• Legal Status: Prescription Only Medicine (POM)