ALEXAN 20MG-1ML VIAL 20 mg/ml Solution for injection/infusion 5ml Vial

Product Overview

Alexan 20mg/ml Solution for Injection/Infusion is a specialized chemotherapy medication containing Cytarabine, an antimetabolite.

Produced by Hikma Pharmaceuticals, this potent agent is crucial in the treatment regimens for various hematological malignancies.

It works by interfering with DNA synthesis, thereby inhibiting the growth of cancer cells.

As a cornerstone in cancer therapy, Alexan is primarily prescribed by oncologists for conditions such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma.

Its administration is strictly managed by healthcare professionals within a clinical setting to ensure patient safety and optimal therapeutic outcomes.

Benefits of Use

• Targeted treatment for specific types of leukemia and lymphoma.
• Helps in achieving remission and prolonging survival in eligible patients.
• An essential component of established chemotherapy protocols.

How to Use

1. Alexan 20mg/ml Solution for Injection/Infusion is intended for intravenous (IV), subcutaneous (SC), or intrathecal administration.
2. It must be prepared and administered by qualified healthcare professionals experienced in oncology.
3. Dosage and administration regimen are highly individualized based on the patient's specific cancer type, stage, body surface area, overall health, and the chemotherapy protocol being followed.
4. Do not attempt to self-administer this medication.
5. Strict adherence to aseptic techniques is required during preparation and administration.

Caution & Warnings

• Alexan is a cytotoxic agent and should only be handled and administered by personnel trained in the safe handling of chemotherapy drugs.
• May cause severe myelosuppression (bone marrow depression), leading to a high risk of infection, bleeding, and anemia.
• Potential for significant gastrointestinal toxicity, including nausea, vomiting, diarrhea, and stomatitis.
• Neurological side effects, including cerebellar toxicity (ataxia, dysarthria) and peripheral neuropathy, can occur, especially with high doses or intrathecal administration.
• Hepatotoxicity (liver damage) can occur; liver function should be monitored regularly.
• Contraindicated in pregnant and breastfeeding women due to potential harm to the fetus or infant.
• Patients should be monitored closely for adverse reactions throughout the treatment period.
• Store below 25°C and protect from light. Do not freeze.
• Dispose of according to local guidelines for cytotoxic waste.

Ingredients

• Active Ingredient: Cytarabine 20 mg/ml
• Excipients: Water for Injection, Hydrochloric Acid (for pH adjustment), Sodium Hydroxide (for pH adjustment).

Product Details

• Brand: Alexan
• Manufacturer: Hikma Pharmaceuticals
• Strength: 20 mg/ml
• Dosage Form: Solution for Injection/Infusion
• Package Size: 5ml Vial
• Therapeutic Class: Antineoplastic (Antimetabolite)
• Legal Status: Prescription Only Medicine (POM)