ADRIBLASTINA 10MG/5ML VIAL 2 Solution for injection Vial

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10331014267

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ADRIBLASTINA 10MG/5ML VIAL contains Doxorubicin Hydrochloride, a powerful chemotherapy agent used to treat various cancers. It is administered intravenously under strict medical supervision. This medication is essential for many oncology treatment protocols and requires careful patient monitoring due to potential side effects.

Details

Product Overview

ADRIBLASTINA 10MG/5ML VIAL is a potent medication used in the treatment of various cancers. This sterile solution is intended for intravenous administration under strict medical supervision. It belongs to the class of anthracycline antineoplastic agents.

Benefits of Use

ADRIBLASTINA (Doxorubicin Hydrochloride) is primarily indicated for the treatment of a wide range of neoplastic conditions. It is effective against certain types of: - Leukemias (e.g., acute lymphoblastic leukemia, acute myeloid leukemia). - Lymphomas (e.g., Hodgkin's lymphoma, non-Hodgkin's lymphoma). - Solid tumors (e.g., breast cancer, ovarian cancer, small cell lung cancer, bladder cancer, thyroid cancer, soft tissue sarcomas, osteosarcoma). Its mechanism involves interfering with DNA replication and repair in cancer cells, leading to their destruction. This medication is a critical component in many chemotherapy regimens.

How to Use

ADRIBLASTINA must be administered by qualified healthcare professionals experienced in the use of cytotoxic agents. It is administered intravenously and typically requires careful dosage calculation based on body surface area. Here are general steps for administration, always under medical guidance:

Ensure patient is properly hydrated before administration.
Administer intravenously over a specified period, as directed by the physician.
Monitor the infusion site closely to prevent extravasation.
Follow all institutional guidelines for safe handling and administration of antineoplastic agents.
Do not mix with other drugs unless compatibility is confirmed by a pharmacist.

Caution & Warnings

Cardiotoxicity: ADRIBLASTINA can cause serious, dose-dependent myocardial toxicity. Cardiac function must be closely monitored before and during treatment.
Myelosuppression: This medication can lead to severe bone marrow suppression, including leukopenia, neutropenia, and thrombocytopenia, increasing the risk of infection and bleeding. Complete blood counts should be performed regularly.
Extravasation Risk: Severe tissue necrosis can occur if extravasation happens during intravenous administration. Immediate action should be taken if extravasation is suspected.
Secondary Malignancies: There is an increased risk of developing secondary acute myeloid leukemia.
Nausea and Vomiting: May cause severe nausea and vomiting; prophylactic antiemetics are often required.
Pregnancy and Breastfeeding: Contraindicated in pregnancy and breastfeeding due to potential harm to the fetus or infant. Effective contraception must be used during treatment and for a period thereafter.
Liver Impairment: Dosage adjustments may be necessary in patients with impaired liver function.
Drug Interactions: Be aware of potential interactions with other medications, especially those affecting cardiac function or metabolism.

Ingredients

Active Ingredient:

Doxorubicin Hydrochloride: 10 mg (equivalent to 9.29 mg doxorubicin base)

Excipients:

Sodium Chloride
Water for Injection

(Specific excipients may vary by formulation, always refer to the product leaflet for full details).

Product Details

Form: Solution for injection
Strength: 10 mg / 5 ml
Package Size: 2 vials
Manufacturer: Pfizer
Legal Status: Prescription Only Medicine (POM)
Storage: Store under refrigeration (2°C - 8°C) and protect from light.

More Information

More Information
Gtin	6-5669-22
Recommended Sale Price	51.75
Is Wasfaty Product	No
Brand	Not Defined
Ingredient Name	DOXORUBICIN HYDROCHLORIDE
SFDA Reg. No	6-5669-22
IBC	6-5669-22
Drug Type	Prescription
Scientific Name	Doxorubicin Hydrochloride
Strength	10
Strength Unit	mg
Form	Solution for injection
Admin Route	Intravenous
Size	5
Size Unit	ml
Package Types	Vial
Package Size	2
Storage conditions	Store unopened vials under refrigeration (2°C to 8°C). Protect from light. Do not freeze.
Refrigerator Storage	Yes